UH Sequencing Core (UH-SEQ)

Recent Publications

  1. Mistretta B, Rankothgedera S, Castillo M, Rao M, Holloway K, Bhardwaj A, El Noafal M, Albarracin C, El-Zein R, Rezaei H, Su X, Akbani R, Shao XM, Czerniecki BJ, Karchin R, Bedrosian I, Gunaratne PH*. Chimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer. Front Immunol. 2023;14:1188831. eCollection 2023. PubMed PMID: 37744342; PubMed Central PMCID: PMC10512078.
  2. Sandra L. Grimm, Emily F. Mendez, Laura Stertz, Thomas D. Meyer, Gabriel R. Fries, Tanmay Gandhi, Rupa Kanchi, Sudhakar Selvaraj, Antonio L. Teixeira, Thomas R. Kosten, Preethi Gunaratne, Cristian Coarfa and Consuelo Walss-Bass. MicroRNA-mRNA networks are dysregulated in opioid use disorder postmortem brain: Further evidence for opioid-induced neurovascular alterations. Front. Psychiatry, 12 January 2023. Sec. Molecular Psychiatry. Volume 13. doi.org/10.3389/fpsyt.2022.1025346
  3. Nicole Prodan, Faheem Ershad, Arfaxad Reyes-Alcaraz, Luge Li, Brandon Mistretta, Lei Gonzalez, Zhoulyu Rao, Cunjiang Yu, Preethi H. Gunaratne, Na Li, Robert J. Schwartz, Bradley K. McConnell. Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells iScience. 2022 Nov 18; 25(11): 105402. Published online 2022 Oct 20. doi: 10.1016/j.isci.2022.105402. PMCID: PMC9646947
  4. Jose Thaiparambil, Jianrong Dong, Sandra L Grimm, Dimuthu Perera, Chandra Shekar R Ambati, Vasanta Putluri, Matthew J Robertson, Tajhal D Patel, Brandon Mistretta, Preethi H Gunaratne, Min P Kim, Jason T Yustein, Nagireddy Putluri, Cristian Coarfa, Randa El-Zein. Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer. Cancer Med. 2022 Jun 8. PMID: 35676822
  5. Sarah E Woodfield, Brandon J Mistretta, Roma H Patel, Aryana M Ibarra, Kevin E Fisher, Stephen F Sarabia, Ilavarasi Gandhi, Jacquelyn Reuther, Zbigniew Starosolski, Andrew Badachhape, Jessica Epps, Barry Zorman, Aayushi P Shah, Samuel R Larson, Rohit K Srivastava, Yan Shi, Andres F Espinoza, Saiabhiroop R Govindu, Richard S Whitlock, Kimberly Holloway, Angshumoy Roy, Pavel Sumazin, Ketan B Ghaghada, Dolores Lopez-Terrada, Preethi H Gunaratne, and Sanjeev A VasudevanHepT1-derived murine models of high-risk hepatoblastoma display vascular invasion, metastasis, and circulating tumor cells. Open Biol. MS ID#: BIOLOPEN/2021/058973 (Accepted)
  6. Divya Ravirala, Brandon Mistretta, Preethi H Gunaratne, Guangsheng Pei, Zhongming Zhao, Xiaoliu Zhang. Co-delivery of novel bispecific and trispecific engagers by an amplicon vector augments the therapeutic effect of an HSV-based oncolytic virotherapy. J Immunother Cancer. 2021; 9(7): e002454. Published online 2021 Jul 6. doi: 10.1136/jitc-2021-002454. PMCID: PMC8261877
  7. Yajuan Li, Zhi Tan, Yaohua Zhang, Zhao Zhang, Qingsong Hu, Ke Liang, Jun Yao, Youqiong Ye, Yi-Chuan Li, Chunlai Li, Lan Liao, Jianming Xu, Zhen Xing, Yinghong Pan, Sujash S. Chatterjee, Tina K. Nguyen, Heidi Hsiao, Sergey D. Egranov, Nagireddy Putluri, Cristian Coarfa, David H. Hawke, Preethi H. Gunaratne, Kuang-Lei Tsai, Leng Han, Mien-Chie Hung, George A. Calin, Fares Namour, Jean-Louis Guéant, Ania C. Muntau, Nenad Blau, V. Reid Sutton, Manuel Schiff, François Feillet, Shuxing Zhang, Chunru Lin, Liuqing Yang. A noncoding RNA modulator potentiates phenylalanine metabolism in mice Science. 2021 Aug 6; 373(6555): 662-673. PMCID: PMC9714245
  8. Yajuan Li, Yaohua Zhang, Qingsong Hu, Sergey D. Egranov, Zhen Xing, Zhao Zhang, Ke Liang, Youqiong Ye, Yinghong Pan, Sujash S. Chatterjee, Brandon Mistretta, Tina K. Nguyen, David H. Hawke, Preethi H. Gunaratne, Mien-Chie Hung, Leng Han, Liuqing Yang, Chunru Lin. Genome Med. 2021; 13: 137. Published online 2021 Aug 28. doi: 10.1186/s13073-021-00937-4. Functional significance of gain-of-function H19 lncRNA in skeletal muscle differentiation and anti-obesity effects. PMCID:PMC8403366
  9. Stewart Fannin, Jonathan Rangel, Abiodun P. Bodurin, Tannon Yu, Brandon Mistretta, Sujina Mali, Preethi Gunaratne, Steven J. Bark, Jerry O. Ebalunode, Arshad Khan, William R. Widger, Mehmet Sen. Functional and structural characterization of Hyp730, a highly conserved and dormancy‐specific hypothetical membrane protein. Microbiologyopen. 2021 Jan; 10(1): e1154. Published online 2021 Feb 3. doi: 10.1002/mbo3.1154. PMCID: PMC7856521
  10. Andrew J. Davis, Maksym Tsinkevich, Jason Rodencal, Hussein A. Abbas, Xiao-hua Su, Young-Jin Gi, Bin Fang, Kimal Rajapakshe, Cristian Coarfa, Preethi H. Gunaratne, John M. Koomen, Kenneth Y. Tsai, Elsa R. Flores. TAp63-regulated microRNAs suppress cutaneous squamous cell carcinoma through inhibition of a network of cell cycle genes. Cancer Res. 2020 Jun 15; 80(12): 2484-2497. PMCID: PMC7299759
  11. Raghunathan S, Islas JF, Mistretta B, Iyer D, Shi L, Gunaratne PH, Ko G, Schwartz RJ, McConnell BK. Conversion of human cardiac progenitor cells into cardiac pacemaker-like cells. J Mol Cell Cardiol. 2020 Jan;138:12-22. doi: 10.1016/j.yjmcc.2019.09.015. Epub 2019 Oct 31. PMID: 31678351
  12. Havis S, Bodunrin A, Rangel J, Zimmerer R, Murphy J, Storey JD, Duong TD, Mistretta B, Gunaratne P, Widger WR, Bark SJ. A Universal Stress Protein that Controls Bacterial Stress Survival in Micrococcus luteus. J Bacteriol. 2019 Sep 23. pii: JB.00497-19. doi: 10.1128/JB.00497-19. PMID: 31548273
  13. Hu Q, Ye Y, Chan LC, Li Y, Liang K, Lin A, Egranov SD, Zhang Y, Xia W, Gong J, Pan Y, Chatterjee SS, Yao J, Evans KW, Nguyen TK, Park PK, Liu J, Coarfa C, Donepudi SR, Putluri V, Putluri N, Sreekumar A, Ambati CR, Hawke DH, Marks JR, Gunaratne PH, Caudle AS, Sahin AA, Hortobagyi GN, Meric-Bernstam F, Chen L, Yu D, Hung MC, Curran MA, Han L, Lin C, Yang L. Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression. Nat Immunol. 2019 Jun 3. doi: 10.1038/s41590-019-0400-7. PMID:31160797
  14. Maria Moreno-Villanueva, Ye Zhang, Alan Feiveson, Brandon Mistretta, Yinghong Pan, Sujash Chatterjee, Winston Wu, Ryan Clanton, Mayra, Nelman-Gonzalez, Stephanie Krieger, Preethi Gunarantne, Brian Crucian, Honglu Wu. Single-cell RNA-sequencing identifies activation of TP53 and STAT1 pathways in human T lymphocyte subpopulations in response to ex vivo radiation exposure. Int. J. Mol. Sci. 2019, ijms-487137
  15. Chen C, Meng Q, Xia Y, Ding C, Wang L, Dai R, Cheng L, Gunaratne P, Gibbs RA, Min S, Coarfa C, Reid JG, Zhang C, Jiao C, Jiang Y, Giase G, Thomas A, Fitzgerald D, Brunetti T, Shieh A, Xia C, Wang Y, Wang Y, Badner JA, Gershon ES, White KP, Liu C. The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Sci Transl Med. 2018 Dec 13. pii: eaat8178. doi: 10.1126/scitranslmed.aat8178. PMID:30545964